Reactivity-based fluoride detection: evolving design principles for spring-loaded turn-on fluorescent probes.
نویسندگان
چکیده
A covalently triggered fluorescence turn-on detection scheme has been implemented for a tris(N-salicylideneamine)-derived dynamic fluorophore. Selective cleavage of strategically placed Si-O bonds by fluoride ion induces spring-loaded conformational transitions that are tightly coupled to fluorescence enhancement.
منابع مشابه
A fluorescent probe for rapid aqueous fluoride detection and cell imaging.
A stable and highly selective fluorescent probe has been designed and synthesized for the rapid detection of fluoride ions (F(-)) in aqueous solution and living cells. The design was based on the high reactivity of F(-) toward a silyl group.
متن کاملRecognition- and Reactivity-Based Fluorescent Probes for Studying Transition Metal Signaling in Living Systems
Metals are essential for life, playing critical roles in all aspects of the central dogma of biology (e.g., the transcription and translation of nucleic acids and synthesis of proteins). Redox-inactive alkali, alkaline earth, and transition metals such as sodium, potassium, calcium, and zinc are widely recognized as dynamic signals, whereas redox-active transition metals such as copper and iron...
متن کاملFluorescent Sensing of Fluoride in Cellular System
Fluoride ions have the important roles in a lot of physiological activities related with biological and medical system, such as water fluoridation, caries treatment, and bone disease treatment. Great efforts have been made to develop new methods and strategies for F(-) detection in the past decades. Traditional methods for the detection of F(-) including ion chromatography, ion-selective electr...
متن کاملRhodamine based dual probes for selective detection of mercury and fluoride ions in water using two mutually independent sensing pathways.
New rhodamine based molecules have been designed as dual probes for the ppb-level selective detection of Hg(2+) and F(-) ions in aqueous medium at physiological pH 7.4. The probes have been designed in such a way to utilize both the properties of the metal ion induced 'turn-on' detection mechanism of the spirolactam ring opening of the rhodamine moiety and the reaction based cleavage of the O-s...
متن کاملDesign of a Fluorescent Sensor Based on the Polydopamine Nanoparticles for Detection of Gallic Acid
Background: Gallic acid (GA) is one of the polyphenolic compounds with antioxidant, antimicrobial and radical scavenging activities, which plays a main role in human health against cancer and cardiovascular diseases. GA concentration can be quantitatively measured in food, medicinal plants and body fluids. Materials and Methods: In this study, MnO2 nanosheets were prepared by reducing potassium...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Organic letters
دوره 9 18 شماره
صفحات -
تاریخ انتشار 2007